Team

• Dr. med. Dr. rer. nat. Yizhu Li (PI)
• Moritz Büscher, Msc., PhD student
• Xiaoyue Shi, Msc. (cand. med., CSC Scholar)
• Shuwen You, Msc. (cand. med., CSC Scholar)
• Yifeng Zhu, Msc. (cand. med., CSC Scholar)
• Yuan Jiang, Msc. cand.
• Muhammad Ramadhani, Msc. cand.

Alumni

• Sabrina Chaabane, Msc.
• Janina Friedrich, Msc.
• Omar Ismail, Bsc.
• Badr Al Khatib, Bsc.
• Yurong Ling, Msc.
• Marina Munker, Bsc.
• Olivia Wan Cheng Oh, Msc.
• Ronja Pientka, Bsc.
• Dragan Sandulovic, Msc.
• Soundarya Shankar, Msc.
• Han Yu, Msc.

Our research investigates the translational application of novel DNA modifications. We utilize the highly specific click chemistry reactions to modify cellular DNA in the cell culture but also in the living mouse. Depending on the added structure, these have a variety of downstream functions such as in differential cellular toxicity and molecular diagnostics. Additional topics of interest include the physiology of DNA damage and repair in response to various chemotherapeutic agents, and the pharmacological control of the cell cycle to induce selective cellular toxicity.

> PubMed

Thesis projects

If you are interested in a Master's thesis in the field of life science, please forward me your application via email (yizhu.li@tum.de).
 

Grant support

• Kommission für Klinische Forschung (KKF)
• Else-Kröner-Fresenius-Stiftung (2021-EKEA.117)
• Deutsche Krebshilfe (70116563)